Hemorheology and blood gas analysis of COPD patients complicated by CI in acute exacerbation time
10.3760/cma.j.issn.1008-6706.2010.11.017
- VernacularTitle:慢性阻塞性肺疾病急性加重期并发脑梗死患者血液流变学及血气分析
- Author:
Huiping RAO
- Publication Type:Journal Article
- Keywords:
Chronic obstructive pulmonary disease;
Cerebral infarction;
Hemorheology;
Blood gas analysis
- From:
Chinese Journal of Primary Medicine and Pharmacy
2010;17(11):1476-1477
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe indicators of hemorheology and blood gas analysis of COPD( chronic obstructive disease) patients complicated by CI(cerebral infarction) in acute exacerbation time and the relationship between them.Methods 46 patients with COPD complicated by CI in acute exacerbation time(complications group) and 44 patients with COPD in acute exacerbation time(COPD group) blood rheology indicators,fibrinogen(Fg) ,D-di-mer(DD) and blood gas analysis were detected.And 45 cases of health-related physical check (control group) were recruited for comparison.Results Compared with the control group,complication group,COPD group of whole blood viscosity,plasma viscosity,hematocrit,platelet adhesion rate,Fg,and DD levels were significantly increased,the difference was significant(P<0.05) ;The complications group of whole blood viscosity,Fg,and DD levels were significantly higher than COPD group;Fg and DD and blood PaCO2 correlated( r Fg =0.36,P<0.01 ,rDD =0.510,P<0.01).Conclusion Patients with chronic obstructive pulmonary disease and cerebral infarction in acute exacerbation time had abnormal coagulation status,and improving ventilation and early application of anticoagulant drug therapy,could reduce the chronic obstructive pulmonary disease,the occurrence of cerebral infarction.
