Significance of serum CD62p level in patients with severe pulmonary contusion

VernacularTitle:早期重度肺挫伤患者测定P选择素的临床意义
Author: Chengfang MA ; Zhihua LI ; Chunyong WEI ; Lixu WANG ; Yi LUO ; Qiongchuan HONG
Publication Type:Journal Article
Keywords: Respiratory distress syrdrome,adult; P-selection; Platelet activation
From: Chinese Journal of Primary Medicine and Pharmacy 2009;16(z1):13-14
CountryChina
Language:Chinese
Abstract: Objective To determine the changes of patients with severe pulmonary contusion and the relationship among the serum level of alpha-granular membrane protein (CD62p), the severity of injury and prognosis. Methods The serum level of CD62p, was measured in 45 patients with severe pulmonary contusion on hour 2, hour 12,day 1,3,7 after injured. Forty-five patients were divided into two groups: the survive group and the death group. The levels of CD62p between two groups were compared. Results The serum levels of CD62p in patients with severe pulmonary contusion on 12 hours, 1,3 days after injury were higher than those on 2 hours (P<0.05). The serum levels of CD62p in the survive group and death group on 2 h, 12 hours after injury were higher than those in the control group(P<0.05), and the serum levels of CD62p in the death group were higher than those in the survive group. Conclusion It was helpful in judging the severity of head in jury and prognosis to determine the serum levels of CD62p in patients with severe pulmonary contusion.