Pregnancy-associated plasma protein-A and ischemic stroke
10.3760/cma.j.issn.1673-4165.2010.005.012
- VernacularTitle:妊娠血浆蛋白-A与缺血性卒中
- Author:
Yongjiu WANG
;
Yan CHENG
- Publication Type:Journal Article
- Keywords:
Pregnancy-associated plasma protein-A;
Atherosclerosis;
Stroke;
Brain ischemia;
Biological markers
- From:
International Journal of Cerebrovascular Diseases
2010;18(5):377-380
- CountryChina
- Language:Chinese
-
Abstract:
Pregnancy-associated plasma protein-A (PAPP-A),a high-molecular-weight zinc-binding metrix metalloproteinase,is expressed abundantly in the ruptured atherosclerostic plaque. PAPP-A can be used as a novel biological marker of plaque instability and cardiovascular events in patients with acute coronary syndrome. However,the role of PAPP-A in iscbemic stroke remains unclear. This article reviews the value of VAPP-A in predicting the risks of ischemic stroke events.
