Clinical study of combined prednisone with minoxidil in treatment of the androgenetic alopecia

VernacularTitle:泼尼松和米诺地尔联合治疗雄激素性秃发临床研究
Author: Fanjun MENG
Publication Type:Journal Article
Keywords: Alopecia; Prednisone; Zinc sulfate; Minoxidil
From: Chinese Journal of Postgraduates of Medicine 2010;33(18):4-6
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinical effect of prednisone and zinc preparation combined with 2％ minoxidil in the androgenetic alopecia. Methods Ninety-eight patients with the androgenetic alopecia were randomly divided into two groups, each group was 49 patients. The treatment group received prednisone and zinc preparation oral solution combined with 2％ minoxidil, the control group received only prednisone and zinc preparation oral solution. The each course of treatment was 3 months, the effect was observed after 1-4 courses of treatment. Results The curative rate of the treatment group and control group were 10.2％( 5/49 ) ,36.7％ (18/49) and 6.1％ (3/49) ,22.4％ (11/49) respectively in 3 and 6 months after treatment, there were no significant difference between two groups (P ＞ 0.05 ). The curative rate of the treatment group and control group were 77.6％ (38/49), 91.8％ (45/49) and 42.9％ (21/49 ), 59.2％(29/49) respectively in 9 and 12 months after treatment, there were significant difference between two groups (P＜ 0.05). Conclusion On treating the androgenetic alopecia, prednisone and zinc preparation combined with minoxidilis effective and safe.