Treatment of femoral head necrosis by core decompression and stem cells transplantation combined with Traditional Chinese Medicine
10.3760/cma.j.issn.1008-6706.2010.11.020
- VernacularTitle:髓芯减压植骨干细胞移植联合中药治疗股骨头坏死
- Author:
Renchun DENG
;
Lan HONG
;
Zhihui HUANG
;
Huaming CUI
- Publication Type:Journal Article
- Keywords:
Femoral head necrosis;
Decompression;
Mesenchymal stem cells transplantation;
Traditional Chinese Medicine;
Curative effect
- From:
Chinese Journal of Primary Medicine and Pharmacy
2010;17(11):1483-1485
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study curative effect of core decompression and autologous bone marrow stem cell transplantation combined with traditional Chinese medicine in the treatment of early femoral head necrosis (ANFH).Methods 30 patients with femoral head necrosis treated by different methods were divided into 3 groups: core decompression A group) 10 cases(12 hips) ;core decompression pus stem cells transplantation(B group) 10 cases(13 hips) ;core decompression pus stem cells transplantation combined with traditional Chinese medicine(C group) 10 ca-ses( 10 hips) ;The X-ray 、CT MRI、Harris score( HHS) .curative effect were observed.Results The phase of Ⅰ,Ⅱ,Ⅲ,in 3 groups didn't appear deformation and collapse at 3,6,12 months;The score of Harris after 12 months 93 points were higher than that preoperatively 57.5 points(χ 2= 5.81 ,P<0.05) ;The signal ratio of femoral head volume in MRI was 42% before treatment,disappearance of femoral head necrosis after treatment;Total curative effect of B,C group,werehighter than that Agroup(χ2 =3.81,χ2 =3.98,P<0.05).Conclusion The operative treatment of ANFH with core decompression and stem cells transplantation combined with traditional Chinese medicine had the advantage of minimal damage,simplicity,accuracy,and effectiveness.