The relationship of serum resistin and pancreatic necrosis in the patients with severe acute partieatitis

VernacularTitle:重症急性胰腺炎患者血清抵抗素水平与胰腺坏死的关系
Author: Yue MA ; Zongwen HUANG ; Qing XIA ; Ping XUE ; Jia GUO ; Hongqiang WEI ; Fuqian HE ; Zhengyu CHENG ; Ziqi LIN
Publication Type:Journal Article
Keywords: Pancreatitis necrotizing; Resistin; ROC curve
From: Chinese Journal of Pancreatology 2010;10(3):168-170
CountryChina
Language:Chinese
Abstract: Objective To investigate the relationship of serum resistin and pancreatic necrosis in the patients with severe acute pancreatitis. Methods Twenty-eight patients with SAP admitted to our hospital from March 2008 to November 2008 were divided into two groups according to the CT scan imaging: necrotic group and non-necrotic group. The enzyme-linked immunosorbent assay (ELISA) was used to test the serum resistin levels. An ROC curve was depicted to predict the pancreas necrosis. Results There were 21 patients in the non-necrotic group and 7 in the necrotic group, and there was no significant difference in terms of sex, age and baseline disease (P>0.05). The resitin levels ranged from 0.1730 ng/ml to 7.4923 ng/ml, with a mean (3.7102±1.6987) ng/ml. The area under the curve of resistin values was 0.884±0.108 (95%CI:0.672～1.097), asymptote signals 0.003, then it was calculated that P=0.003, which was>0.50. Conclusions The serum resistin may be of clinical value to predict the pancreatic necrosis.