Brachial-ankle pulse wave velocity is a predictor of recurrent cardiovascular events in elderly male patients with acute coronary syndrome
10.3760/cma.j.issn.0254-9026.2010.06.002
- VernacularTitle:肱踝脉搏波速度对老年男性急性冠状动脉综合征后再发心血管事件的预测价值
- Author:
Ning SUN
;
Gexin ZHU
;
Hui WANG
;
Jianli TIAN
;
Yanhong WU
;
Yun ZHANG
- Publication Type:Journal Article
- Keywords:
Pulse;
Coronary disease;
Atherosclerosis
- From:
Chinese Journal of Geriatrics
2010;29(6):443-447
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore whether brachial-ankle pulse wave velocity (baPWV) can be used as a predictor of recurrent cardiovascular events in elderly male patients with acute coronary syndrome (ACS). Methods The baPWV and biochemical indicators were measured in 118 elderly men with ACS, aged 61-92 years (mean age 76.6±6.7 years). During the follow-up period (617±297 days), all cardiovascular events (unstable angina, heart failure, cardiac death and stroke, etc.)were recorded. Results The baPWV was (17.48±3.54)m/s in non-event group(n=90),(21.91±4.86) m/s in event group and (24.48±4.39) m/s in major endpoint event group, respectively (both P<0. 05). There were 30 cardiovascular events that occurred in 28 patients, including 12 major endpoint events. The receiver operating characteristic curve demonstrated that the cut-off point of baPWV for predicting a cardiovascular event was 19.51 m/s and that for predicting a major endpoint event was 20.52m/s. The multivariate Cox proportional hazards model demonstrated that the above cut-off points had significantly relative risk for cardiovascular event: 1.37(95% CI: 1.16-1.63)and for major event:1.71(95% CI: 1.23-2.36). Conclusions The baPWV can be used as a predictor of recurrent cardiovascular events in elderly men with ACS.