Increasing Carbapenem-Resistant Gram-Negative Bacilli and Decreasing Metallo-beta-Lactamase Producers over Eight Years from Korea.
10.3349/ymj.2015.56.2.572
- Author:
Yangsoon LEE
1
;
Chang Ki KIM
;
Hae Sun CHUNG
;
Dongeun YONG
;
Seok Hoon JEONG
;
Kyungwon LEE
;
Yunsop CHONG
Author Information
1. Department of Laboratory Medicine, Hanyang University College of Medicine, Seoul, Korea.
- Publication Type:Brief Communication ; Research Support, Non-U.S. Gov't
- Keywords:
Gram-negative bacilli;
carbapenem;
metallo-beta-lactamase
- MeSH:
Acinetobacter/classification/drug effects/*enzymology;
Acinetobacter Infections/drug therapy;
Anti-Bacterial Agents/*pharmacology;
Bacterial Proteins;
Carbapenems/*pharmacology;
Drug Resistance, Microbial;
Gram-Negative Bacteria/*drug effects/enzymology/isolation & purification;
Humans;
Incidence;
Microbial Sensitivity Tests/trends;
Population Surveillance;
Pseudomonas/classification/drug effects/enzymology;
Republic of Korea/epidemiology;
beta-Lactamases/biosynthesis/*drug effects
- From:Yonsei Medical Journal
2015;56(2):572-577
- CountryRepublic of Korea
- Language:English
-
Abstract:
The trends and types of carbapenemase-producing Gram-negative bacilli were analyzed from clinical specimens collected between 2005 and 2012 at a Korean teaching hospital. The proportions of carbapenem-resistant Acinetobacter spp. increased markedly to 66%. Metallo-beta-lactamase producers significantly decreased and the majority shifted from the bla(VIM-2) type to the bla(IMP-1) type.
