Bronchiolitis Obliterans Associated with Stevens-Johnson Syndrome: A Case Report.
10.3349/ymj.2015.56.2.578
- Author:
Hyungchul PARK
1
;
Young Bo KO
;
Hyouk Soo KWON
;
Chae Man LIM
Author Information
1. Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
- Publication Type:Case Reports
- Keywords:
Stevens-Johnson syndrome;
bronchiolitis obliterans;
dyspnea
- MeSH:
Anti-Bacterial Agents/therapeutic use;
Bronchiolitis Obliterans/etiology/*radiography/therapy;
Bronchoscopy;
Dyspnea/*complications;
Fatal Outcome;
Humans;
Male;
Middle Aged;
Radiography, Thoracic;
Respiratory Distress Syndrome, Adult/*etiology/therapy;
Respiratory Function Tests;
Roxithromycin/therapeutic use;
Stevens-Johnson Syndrome/*complications/drug therapy;
Tomography, X-Ray Computed/methods;
Tracheostomy
- From:Yonsei Medical Journal
2015;56(2):578-581
- CountryRepublic of Korea
- Language:English
-
Abstract:
We report a case of bronchiolitis obliterans associated with Stevens-Johnson syndrome. A 59-year-old man presented with respiratory distress that gradually worsened over 3 months. He had been diagnosed with Stevens-Johnson syndrome 3 months before admission. He had no history of previous airway disease. On physical examination, expiratory breathing sounds were not audible, and a chest X-ray revealed a hyperinflated lung. A pulmonary function test indicated a severe obstructive pattern. Computed tomography scans of inspiratory and expiratory phases of respiration showed oligemia and air trapping, and both were more prominent on expiration view than on inspiration view. The pathogenesis of bronchiolitis obliterans associated with Stevens-Johnson syndrome is largely unknown.
