Early event-related potentials changes during early face processing of mild cognitive impairment patients by face-specific
10.3760/cma.j.issn.1674-6554.2010.02.013
- VernacularTitle:轻度认知障碍患者早期面孔加工的事件相关电位研究
- Author:
Yuanyuan ZHANG
;
Xiuyan LI
;
Mi LI
;
Qinghui MENG
- Publication Type:Journal Article
- Keywords:
Mild cognitive impairment;
Event-related potentials(ERP);
Face perception
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2010;19(2):133-135
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study early face processing of mild cognitive impairment patients by using ERP method．Methods Sixteen healthy old man(normal group)and sixteen mild cognitive impairment patients(MCI group)served as subjects in experiment．Two runs of 300 stimuli(duration：50ms)of 3 facial and 3 non-facial pictures were randomly presented with equal probability(ISI：from 1000ms to 1500ms randomly)，and the subjects were asked to react to facial stimuli and non-facial stimuli by pressing the left button and risht button respectively as quickly as possible．Thirty-two channels electroencephalogram(EEG)Was recorded by Neuroscan Nuamps Systern．Results 1)Specific-face component N170 was found in both groups．Which was distributed at the temporal-occipital region．2)Compared with N170 in normal group，N170 amplitude Was significantly lower((-4．42±0．28)Μv vs(-7．00±0．28)Μv，F=41．52，P<0．01)at temporal-occipital region and delayed((158．91±2．17)ms vs(140．97±2．17)ms，F=34．09，P<0．01) in mild cognitive impairment group．Conclusion The early face processing mechanism of mild cognitive impairment patients may be different from normal people．
