Significance of postoperative transcatheter arterial chemoembolization in high-risk patients with hepatocellular carcinoma

VernacularTitle:肝癌术后复发高危患者行TACE的意义
Author: Fan HUANG ; Xiaoping GENG ; Fubao LIU ; Hongchuan ZHAO ; Guobin WANG ; Yijun ZHAO
Publication Type:Journal Article
Keywords: Carcinoma,hepatocellular; Neoplasm recurrence,local; TACE
From: Chinese Journal of General Surgery 2010;25(6):490-492
CountryChina
Language:Chinese
Abstract: Objective To investigate the effect of postoperative prophylactic transcatheter arterial Chemoembolization(TACE) on preventing recurrence in 54 high-risk patients with hepatocellular carcinoma.Methods These 54 HCC cases were greded as high risk for recurrence and put on close follow up after radical resection.Risk factors included tumor thrombus,cancer satellite or multiple cancer nodules,postoperative high AFP level.Among them 42 cage (target group) received TACE,in which liver function was of Child A,and hepatitis virus replication was controlled in 1000 copies/ml.12 cases(centrol group) didn't receive TACE.The recurrent rate of HCC was compared between the cases with prophylactic TACE and those without through two years of follow-up. Result The recurrence rate of HCC was significantly lower in the cases with prophylactic TACE(19.O%) than those without(50%) within 1 year after the radical operation,and 2 years (52.3% vs 83.3%). Conclusion Postoperative TACE contributes to reducing the short-term HCC recurrence rate.