Analysis of Helicobacter pylori infection status in type 2 diabetes mellitus
10.3760/cma.j.issn.1673-4904.2010.19.002
- VernacularTitle:2型糖尿病幽门螺杆菌感染情况分析
- Author:
Yanguang XU
;
Xinyu LIU
;
Xiaoyi ZHU
;
Lei GUO
;
Shaozhen WANG
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus,type 2;
Helicobacter pylori;
Infection
- From:
Chinese Journal of Postgraduates of Medicine
2010;33(19):3-5
- CountryChina
- Language:Chinese
-
Abstract:
Objective To comprehend the status of Helicobacter pylori (Hp) infection in type 2 diabetes mellitus (T2DM) patients, and study the relationship between Hp and T2DM. Methods Seven hundred and sixty-eight in-hospital T2DM patients (T2DM group, including new diagnosed 194 patients and re-diagnosed 574 patients) and 172 sex, age matched health individuals(control group ) were involved in this study. 14C-urea breath test (14C-UBT) was proceeded in both groups to determine Hp infection, and infection rates were calculated. Results Total Hp infection rate in T2DM group was significantly higher than that in control group [56.0%(430/768) vs 37.8%(65/172) ,P< 0.01], delamination analysis according to sex also showed significant differences between T2DM group and control group(P < 0.01). The rate of Hp infection in new diagnosed patients and re-diagnosed patients, female patients and male patients had no significant difference (P > 0.05 ). The rate of Hp infection in different age and sex had no significant difference (P >0.05 ). Conclusions The rate of Hp infection in T2DM patients is higher than that in non-T2DM patients.Hp infection has relationship with T2DM, and has no relationship with age, sex and course of disease.