Stroke volume variation in the evaluation of fluid responsiveness in refractory septic shock
10.3760/cma.j.issn.0578-1426.2010.07.017
- VernacularTitle:每搏量变异评价顽固性感染性休克患者容量反应性
- Author:
Hongmin ZHANG
;
Dawei LIU
;
Xiaoting WANG
;
Xi RUI
;
Hao WANG
;
Huaiwu HE
;
Ye LIU
;
Xiukai CHEN
- Publication Type:Journal Article
- Keywords:
Stroke volume variation;
Shock,septic;
Fluid responsiveness
- From:
Chinese Journal of Internal Medicine
2010;49(7):610-613
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate fluid responsiveness by stroke volume variation (SVV) in mechanically ventilated patients with refractory septic shock.Methods Forty-two refractory septic shock patients were enrolled in the study.According to the responsiveness of fluid loading, the patients were divided into responsive group and non-responsive group.The SVV values of two groups were retrospectively analyzed.The receiver operating characteristic curve was drafted to determine the cut-off value of SVV for predicting fluid responsiveness.Results Among the 42 refractory septic shock patients, 24 were found responsive to fluid loading, 18 were not;before the fluid loading, central venous pressure, heart rate, mean arterial pressure and global end-diastolic volume index in the both groups showed no significant differences whereas the SVV in the responsive group was much higher than that in the nonresponsive group (P =0.006).Using SVV ≥ 12% as the threshold to predict fluid responsiveness, the sensitivity was 77%,specificity was 85%.Conclusion SVV can accurately predict fluid responsiveness in refractory septic shock patients.
