Hashimoto's disease concomitant with thyroid carcinoma
10.3760/cma.j.issn.1007-631X.2010.03.016
- VernacularTitle:桥本病合并甲状腺癌的诊治体会
- Author:
Zhongmin DI
;
Min YAN
- Publication Type:Journal Article
- Keywords:
Thyroiditis,autoimmune;
Thyroid neoplasms;
Surgical procedures,operative
- From:
Chinese Journal of General Surgery
2010;25(3):224-226
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diagnosis and treatment of Hashimoto's diseaseconcomitant with thyroid carcinoma. Methods Clinical data of 74 cages of thyroid carcinoma occuring on the background of Hashimoto's disease were retrospectively analyzed. Results All cases were papillary carcinoma pathologically.The serum TGAb and McAb level elevated in 56 and 68 cases,respectively.While TPOAB level was all elevated.45 cages underwent unilateral thyroideetomy and contralateral subtotal thyroidectomy,1 case did bilateral near total thyroidectomy,26 cases did unilateral thyroidectomy.and 2 cases with bilateral thyroidectomy.All cases underwent combined central region lymph nodes dissection(positive rate was 27%,20/74),10 cases underwent modied lymph node resection.69 cases were followed up rangins from 1 month to 7 years,with median length of 29 months.4 cases were re-admired for modified lymph nodes resection. Conclusion TGAb、McAb、FNAB and ultrasound is the main procedure forscreening Hashimoto's disese accompanied with thyroid carcinoma preoperatively.Radical thyroideetomy iS the therapy of choice.