Effect of weight loss on metabolic parameters in over-weight or obesity patients combined with impaired glucose tolerance
10.3760/cma.j.issn.1674-0815.2010.03.006
- VernacularTitle:减轻体重对伴有糖耐量受损的超重及肥胖者代谢指标的影响
- Author:
Yanjun LIU
;
Ting XIAO
;
Ping ZHU
;
Yuxia CHENG
;
Xiaoping YANG
;
Dongping CAO
;
Zhangrong XU
- Publication Type:Journal Article
- Keywords:
Overweight;
Obesity;
Metabolism
- From:
Chinese Journal of Health Management
2010;04(3):142-144
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effective of weight loss on blood glucose,lipid profile,and blood pressure in over-weight or obesity patients combined with impaired glucose tolerance(IGT).Methods Body weight of 91 over-weight or obesity IGT patients were managed by doctors and nurses.Body weight,waist circumference,blood glucose,lipid profile,blood pressure and liver function of the patients were compared at 3 months with baseline.Results After 3 months' intervention,the levels of body weight,waist circumference,fasting plasma glucose,postprandial glucose,systolic blood pressure,diastolic blood pressure,and glutamie oxalacetie transaminase (COT),instead of triglyeeride and hish-density lipoprotein cholesterol (HDL-C),were significantly reduced.Over weight or obesity IGT patients saw a 1.8 and 2.3 kg body weight loss,respectively.Decreased plasma glucose and blood pressure were found both in the over-weight group and in the obesity groups,but decreased waist circumference and GOT were found only in the over-weight patients.Conclusions Body-weight control may improve the blood glucose,blood pressure,central obesity,or fatty liver in over weight or obesity IGT patients.For those obesity patients,longer and stronger body weight control should be needed.
