Relationship of mean color vessels density and microvessel density in rectal cancer and their clinical significance

VernacularTitle:直肠癌彩色血流平均密度与微血管密度的相关性及其临床意义
Author: Zhibin QIAO ; Weihua YE ; Yuzhen ZHAO
Publication Type:Journal Article
Keywords: Endosonography; Rectal neoplasms; Mean color vessels density; Microvessel density
From: Chinese Journal of Ultrasonography 2010;19(6):503-505
CountryChina
Language:Chinese
Abstract: Objective To explore the relationship of the mean color vessels density (MCVD) and pathologic microvessel density(MVD) in rectal cancers and their relation with T stags and lymph node metastasis.Methods MCVD were caculated preoperationly with transrectal color power angiography(TRCPA).After operation MVD was assessed immunohistochemically using anti-CD105 monoclonal antibody.The relationships within MCVD, MVD and T stages and lymph node metastasis were analysed.Results There were positive correlation between MCVD and MVD (r=0.763, P＜0.01) in rectal cancer.There were significant difference of MCVD and MVD in both the depth of carcinoma invasion and metastasis of lymphatic nodes( P＜0.05).Conclusions MCVD can display features of the blood supply and distribution of pathologic microvessels and reflect the development of rectal cancers.MCVD is a credible index to choose available treatment and to evaluate prognosis before operation of rectal cancer.