The regulatory roles of microRNAs in neurogenesis
10.3760/cma.j.issn.1673-4165.2010.06.012
- VernacularTitle:微小RNA在神经发生中的调控作用
- Author:
Changfu PAN
;
Yang WANG
;
Zhifeng DENG
- Publication Type:Journal Article
- Keywords:
MicroRNAs;
Neurogenesis;
Stem cells;
Brain ischemia;
Cell differentiation
- From:
International Journal of Cerebrovascular Diseases
2010;18(6):456-461
- CountryChina
- Language:Chinese
-
Abstract:
Neurogenesis refers to a biological process of neural stem cells self-proliferate and differentiate into new neurons, and are integrated into the neural networks, including the embryonic neurogenesis and adult neurogenesis. Studies have suggested that microRNAs (miRNAs) play vital regulatory roles in neurogenesis. This article reviews the molecular mechanisms of miRNAs in the regulation of embryonic and adult neurogenesis as well as the possible regulatory roles of miRNAs in the process of neurogenesis after cerebral ischemia.
