mTOR signaling pathway and digestive system cancers
10.3760/cma.j.issn.1673-422X.2010.04.010
- VernacularTitle:mTOR信号通路与消化系统肿瘤
- Author:
Zhixin XUE
- Publication Type:Journal Article
- Keywords:
Antineoplastic agents;
Digestive system neoplasms;
mTOR protein
- From:
Journal of International Oncology
2010;37(4):269-272
- CountryChina
- Language:Chinese
-
Abstract:
Deregulated mTOR signaling pathway is associated closely with variety of human cancers. Preclinical and clinical studies of both classical and newly developed mTOR inhibitors in digestive system cancers show that these drugs not only have anti-tumor properties, but also can enhance tumor cells sensitivity to standard chemotherapy agents.
