Decorin and signaling pathways of cancer
10.3760/cma.j.issn.1673-422X.2010.05.004
- VernacularTitle:核心蛋白聚糖与肿瘤信号通路
- Author:
Fenfen ZHANG
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Signaling pathway
- From:
Journal of International Oncology
2010;37(5):332-335
- CountryChina
- Language:Chinese
-
Abstract:
Decorin is a member of small leucine - rich proteoglycan( SLRP) family. Decorin plays an important role in proliferation, differentiation, and migration of carcinoma cells by regulating virous signaling pathways. Decorin will be a novel target for cancer therapy for its role such as regulating cytokines, immunosupression,and inhibiting cancer cells growth and metastasis.