Tumor dormancy and angiogenesis
10.3760/cma.j.issn.1673-422X.2010.05.005
- VernacularTitle:肿瘤休眠与血管新生
- Author:
Xiaohui YAN
- Publication Type:Journal Article
- Keywords:
Tumor dormancy;
Neovascularization,pathologic
- From:
Journal of International Oncology
2010;37(5):335-338
- CountryChina
- Language:Chinese
-
Abstract:
Tumor dormancy is a well-known clinical phenomenon and the underlying mechanisms are poorly understood.It has been speculated that one of the major factors accounting for the dormant behavior is impaired angiogenesis.As stimuli result in the imbalanced concentration between the pro-angiogenic factors and anti-angiogenic factors,the tumors would escape from dormancy.However,why a dormant(silent)tumor be-comes angiogenic has not been explained and the molecular events that participate in it are under investigation.Despite all that,anti-angiogenic therapy is a very promising strategy to induce tumor dormancy.
