Physiopathological action of connexin in kidney
10.3760/cma.j.issn.1673-4408.2010.04.018
- VernacularTitle:间隙连接蛋白在肾脏的病理生理作用
- Author:
Bin WANG
- Publication Type:Journal Article
- Keywords:
Connexin;
Mesangial cell;
Podocytes;
Renal vasculature
- From:
International Journal of Pediatrics
2010;37(4):390-392
- CountryChina
- Language:Chinese
-
Abstract:
As a kind of inherent membrane surface molecules of our human body,connexins are closely related to the cell growth,proliferation and differentiation,which are highly expressed in kidney.Many kidney diseases have a close relationship with connexins' altered expression and disordered function.This paper is dedicated to review the characteristics of connexins molecules,the expression and corresponding functions in the kidney tissues,as well as the possible regulation mechanisms in the kidney tissues in order to explore their applications and value in medical study.