Epigenetic regulation of microRNA and cancer
10.3760/cma.j.issn.1673-422X.2010.04.001
- VernacularTitle:微RNA的表观遗传调控与肿瘤
- Author:
Daochuan LI
;
Qi WANG
- Publication Type:Journal Article
- Keywords:
MicroRNAs;
Neoplasms;
DNA methylation;
Histone acetylation
- From:
Journal of International Oncology
2010;37(4):243-245
- CountryChina
- Language:Chinese
-
Abstract:
Abnormal expression of microRNA (miRNA) and aberration epigenetic regulation can both contribute to cancer development. miRNA expression can be changed by epigenetic regulation such as DNA methylation and histone acetylation, thereby regulates relative oncogenes and tumor-suppressor genes, and consequently leads to carcinogenesis.
