The apoptosis pathways in viral myocarditis
10.3760/cma.j.issn.1673-4408.2010.04.008
- VernacularTitle:凋亡相关细胞信号传导通路与病毒性心肌炎
- Author:
Yongmei SUN
- Publication Type:Journal Article
- Keywords:
Apoptosis;
Signal transduction pathway;
Viral myocarditis
- From:
International Journal of Pediatrics
2010;37(4):359-362
- CountryChina
- Language:Chinese
-
Abstract:
Viral myocarditis(VMC) has been threatening children's health severely.Its mechanisms are not completely clear and lack of dependable therapeutic methods.Studies have demonstrated that apoptosis occurs in VMC.The apoptosis pathways including death-receptor pathway and mitochondrial-mediated pathway participate in cardiocytes apoptosis in VMC.Endoplasmic reticulum pathway is a novel apoptosis pathway that takes part in cardiocytes apoptosis causing by other stress.And crosstalk exists in the three pathways.It may be of potential therapeutic value that these apoptosis pathways could be harnessed.
