Advances in gene expression profiling of breast cancer
10.3760/cma.j.issn.1673-422X.2010.04.017
- VernacularTitle:乳腺癌基因表达谱研究进展
- Author:
Jiangang YU
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Gene expression profiling;
Prognosis
- From:
Journal of International Oncology
2010;37(4):290-293
- CountryChina
- Language:Chinese
-
Abstract:
Breast cancer should be considered as a family of diseases which are significantly different from each other in molecule level rather than a single disease, and clinical heterogeneity of breast cancer origins from molecular heterogeneity. Gene-expression signatures have been developed based on gene expression profiling of breast cancer, such as the 70-gene signature, 21 -gene signature and intrinsic subtypes of breast cancer. These signatures are valuable and have a good prospect in prognosis predicting and clinical decision of breast cancer.
