Evaluation of contrast-enhanced transrectal ultrasound in differential diagnosis of prostate cancer and benign prostatic hyperplasia
10.3760/cma.j.issn.1004-4477.2010.07.017
- VernacularTitle:经直肠前列腺超声造影在鉴别诊断前列腺癌与前列腺增生中的价值
- Author:
Xiang FEI
;
Jie TANG
;
Yanmi LI
;
Yan ZHANG
;
Huaiyin SHI
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Microbubbles;
Prostatic neoplasms;
Prostatic hyperplasia
- From:
Chinese Journal of Ultrasonography
2010;19(7):596-599
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the application of contrast-enhanced transrectal ultrasound ( CETRUS) to identify prostate cancer(PCa) from benign prostatic hyperplasia(BPH). Methods A total of 86 patients with focal prostatic disease detected by trans rectal ultrasound(TRUS) were enrolled in this study.Each patient underwent grey-scale TRUS, CE-TRUS, and targeted-biopsy of prostateunder ultrasound guidance successively on the same day. The criteria of perfusion pattern would be statistically analyzed among groups divided by pathological findings. Every patient's images of CE-TRUS were observed and features of perfusion pattern were recorded by two doctors who were blind to any clinical data of patient.Then these features recorded by two doctors were compared, if the features were coherent, they would be recorded as final results,and otherwise two doctors would consult till the features were coherent. Results Compared with BPH group, the enhancement features of PCa group were rapid enhancement, increased enhancement, heterogeneous enhancement, well-defined boundary of lesion after enhancement, asymmetric appearance of intraprostatic vessels, rapid decrease, perfusion defect areas within lesions and the roughly discontinuous juncture between enhancement and no enhancement area within lesions. Conclusions There was significant difference in enhancement pattern between BPH and PCa groups, observing enhancement pattern could help to identify prostate cancer from benign prostate hyperplasia.
