The relationship among plasma visfatin,endothelin, and insulin resistance in type 2 diabetic patients before and after treatment
10.3760/cma.j.issn.1000-6699.2010.07.018
- VernacularTitle:2型糖尿病患者治疗前后内脂素与内皮素及胰岛素抵抗的关系
- Author:
Gu GAO
;
Qian LI
;
Lu YUAN
;
Bo DING
;
Huiqin LI
;
Jianhua MA
;
Shaokang QI
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus,type 2;
Visfatin;
Endothelin;
Insulin resistance;
Insulin glargine
- From:
Chinese Journal of Endocrinology and Metabolism
2010;26(7):588-590
- CountryChina
- Language:Chinese
-
Abstract:
The relationship between visfatin.endothelin, and insulin resistance in the pathogenesis of type 2 diabetes mellitus was explored. Endothelin, visfatin, and other markers were compared. Plasma visfatin was reduced after therapy. Endothelin was positively correlated with fasting insulin, HOMA-IR, HOMA-p, and visfatin. Visfatin was positively correlated with endothelin, HbA1C , fasting insulin, and HOMA-IR. HOMA-IR was an independent related factor in influencing visfatin. The visfatin is related to endothelin and insulin resistance, which may contribute to the pathogenesis of insulin resistance and type 2 diabetes mellitus.
