Recent progress in diagnosis and treatment of carcinomatous meningitis
10.3760/cma.j.issn.1673-422X.2010.05.014
- VernacularTitle:脑膜转移癌诊疗现状
- Author:
Shuai YI
- Publication Type:Journal Article
- Keywords:
Meningeal neoplasms;
Cerebrospinal fluid;
Drug therapy;
Radiotherapy
- From:
Journal of International Oncology
2010;37(5):365-368
- CountryChina
- Language:Chinese
-
Abstract:
Carcinomatous meningitis (CM) represents a devastating metastatic complication of malignant tumour, and the incident of CM is increasing in recent years. The diagnosis is made by both cerebrospinal fluid by lumbar puncture and radiological investigation, mainly magnetic resonance imaging. The therapeutic management of CM includes intrathecal administration of chemotherapy, radiotherapy, surgery and palliative care, but the treatment of CM remains controversial Individualized treatment and combined modality therapy are recommended at present, and the utilization of targeted drug may increase therapeutic effect of CM.