Research advancement on triple negative breast cancer
10.3760/cma.j.issn.1673-422X.2010.05.016
- VernacularTitle:三阴乳腺癌研究进展
- Author:
Lu LIU
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Triple negative;
Clinical feature;
Prognosis;
Therapy
- From:
Journal of International Oncology
2010;37(5):371-375
- CountryChina
- Language:Chinese
-
Abstract:
Triple negative breast cancer(TNBC) is defined by the lack of estrogen receptor (ER) , progesterone receptor (PR) and human epidermal growth factor receptor-2 ( Her-2) expression. It is a subtype of tumor with distinct clinical and pathologic features and lacks effective targeted therapies. It is non - sensitive to endocrine therapy and targeted therapy drug herceptin, leaving chemotherapy as the mainstay of treatment The feature and the treatment of TNBC is the hotspot of resent research.
