Melanocortin 4 receptor and children obesity
10.3760/cma.j.issn.1673-4408.2010.04.030
- VernacularTitle:黑皮素4受体与儿童肥胖
- Author:
Jianfang CHU
- Publication Type:Journal Article
- Keywords:
Obesity;
Melanocortin 4 receptor;
Gene mutation
- From:
International Journal of Pediatrics
2010;37(4):427-429
- CountryChina
- Language:Chinese
-
Abstract:
Mutations in the melanocortin 4 receptor (MC4R) represent the most common known cause of monogenic human obesity.MC4R is a family of the five melanocortin receptors.It is an exon lying on chromosome 18.Studies have proved that there is a closed relationship between MC4R and weight regulation.MC4R mutation can result in severer adolescent obesity.
