Indicating significance of Ki-67 in therapy and prognosis of breast cancer
10.3760/cma.j.issn.1673-422X.2010.05.017
- VernacularTitle:Ki-67对早期乳腺癌治疗和预后的指导意义
- Author:
Tingting LIU
- Publication Type:Journal Article
- Keywords:
Ki-67 antigen;
Breast neoplasms
- From:
Journal of International Oncology
2010;37(5):375-377
- CountryChina
- Language:Chinese
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Abstract:
Ki-67,as one kind of nucleoantigen expressed in proliferated cells, has positive correlation with clinical stage, nodal status and Her-2,while negative correlation with estrogen receptor(ER). High Ki-67 expression influnced by endocrine therapy and chemotherapy indicates good proliferative activity. Ki-67, also as an independent prognostic factor of early breast cancer, provides prognostic information combined with other biologic markers. Ki-67 gives additional information breast cancer prognosis staging.
