Prognostic indicators in gastric cancer patients underwent radical resectioa
10.3760/cma.j.issn.1008-6315.2010.07.018
- VernacularTitle:胃癌根治术257例预后多因素分析
- Author:
Wei LIU
;
Ren YANG
;
Wentao ZHANG
;
Lin GUO
- Publication Type:Journal Article
- Keywords:
Gastric cancer radical resection;
Prognosis;
Multivariate analysis
- From:
Clinical Medicine of China
2010;26(7):723-726
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the prognostic indicators in gastric cancer patients underwent radical resection.Methods Clinical data of 257 patients with gastric cancer underwent radical resection from Jan. 2003 to Oct. 2008 in our hospital were analyzed retrospectively. Univariate analysis using Kaplan-Meier analysis and log-rank analysis,multivariate analysis using COX proportion risk model were performed. Results Univariate analysis indicated that tumor site (P <0. 05) .Borrmann type (P <0. 01) .histological type (P <0. 01),depth of infiltration (P < 0. 01 ) , lymph node metastasis rate ( P < 0. 01 ) , tumor size ( P < 0. 01 ) ,complication ( P < 0. 01 ) and accessorial chemotherapy (P<0. 01) influenced the patients' prognosis. Cox regression analysis indicated that lymph node metastasis rate, depth of infiltration, Borrmann type and tumor size were the independent risk factors of prognosis(P<0. 05). The relative risk will increase 3.374 times,2. 337 times,1.657 times and 1.580 times with each additional level of lymph node metastasis, depth of infiltration, Borrmann type and tumor size. Conclusions There are various factors influencing the prognosis of gastric cancer,of which lymph node metastasis rate is the most important prognosis indicator.
