A randomized controlled trial of laparoscopic vs open radical nephrectomy for renal cancer
10.3760/cma.j.issn.1000-6702.2010.07.005
- VernacularTitle:腹腔镜下与开放性根治性肾切除术的前瞻性随机对照研究
- Author:
Jun YAN
;
Hui YU
;
Mingang YING
;
Dong ZHOU
;
Xia CHEN
;
Luchuan CHEN
;
Wenfei YE
;
Weidang ZANG
;
Chunkang YANG
;
Xiaojing CHEN
;
Lingping WANG
- Publication Type:Journal Article
- Keywords:
Kidney neoplasms;
Radical nephrectomy;
Laparoscopes
- From:
Chinese Journal of Urology
2010;31(7):449-451
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the therapeutic outcomes between laparoscopic radical Rephrectomy and open radical nephrectomy for renal cancer. Methods A prospective randomized controlled trial was performed in Fujian Provincial Tumor Hospital from January 2006 to July 2009.Sixty-two cases were randomly divided into 2 groups:laparoscopic radical nephrectomy and open radical nephrectomy.Primary outcome(post-operative hospital stay)and second outcome(estimated blood loss,operative time,incision length,post-operative complications,recurrence,metastasis and survival)were compared between 2 groups. Results Post-operative hospital stay was(5.4±1.3)d in laparoscopic group and(8.1±2.2)d in open group(P<0.05).Median estimated blood loss was 100 ml in laparoseopic group and 200 ml in open group(P<0.05).There were no significant difference between teh 2 groups in operative time,post-operative complications,recurrence,metastasis and survival rates(P>0.05). Conclusion Laparoscopic nephrectomy could reduce hospital stay,which provides a minimally invasive approach for renal cancer.