Combined Aspergillus and Mucor infections in the surgical site after liver transplantation
10.3760/cma.j.issn.1007-631X.2010.07.020
- VernacularTitle:肝移植术后手术部位曲霉菌及毛霉菌感染临床分析
- Author:
Lei LEI
;
Chang LIU
;
Shi HUANG
;
Xiaogang ZHANG
;
Jianhui LI
;
Bo WANG
;
Xuemin LIU
;
Liang YU
;
Yi Lü
- Publication Type:Journal Article
- Keywords:
Liver transplantation;
Aspergillosis;
Mucormycosis;
Surgical wound infection
- From:
Chinese Journal of General Surgery
2010;25(7):569-571
- CountryChina
- Language:Chinese
-
Abstract:
Objective To report the combined Aspergillus and Mucor infections in surgical site after orthotopic liver transplantation. Methods We retrospectively analyzed clinical data of two liver transplantation recipients suffering from postoperative combined Aspergillus and Mucor infections and evaluate the symptoms, diagnosis and treatment. Results In the first patient the graft arteries suddenly ruptured on the 8th day postop caused by Aspergillus and Mucor infection failing an emergency surgical rescue. The patient eventually died of multiple organ failure. In the second recipient deep surgical site infection was diagnosed on the 10th day postop. Combination infection of Aspergillus and Mucor was identified by pathology. Despite of aggressive anti-fungal treatment and support, the general condition continued to deteriorate and the patient eventually died of systemic severe infection and respiratory failure. Conclusion Combined Aspergillus and Mucor infections in operative location is a rare complication of liver transplantation, which was usually occult in onset, and the prognosis is poor.
