Advance of study on cancer stem cell niche
10.3760/cma.j.issn.1673-422X.2010.05.003
- VernacularTitle:肿瘤干细胞niche的研究进展
- Author:
Hao XU
;
Zhixiong LIN
- Publication Type:Journal Article
- Keywords:
Neoplastic stem cells;
Ecosystem
- From:
Journal of International Oncology
2010;37(5):329-332
- CountryChina
- Language:Chinese
-
Abstract:
Cancer stem cell niche provides a relatively stable microenvironment for cancer stem cell (CSC)existence,proliferation and differentiation.This microenvironment consists of kinds of cells,stroma and cytokines, etc. Within it , CSC can resist chemoradiotherapy. It has been shown that destruction of the microen vironment can significantly enhance the effect of chemoradiotherapy and improve prognosis of cancer patients.
