Progress of tumor markers of children's germ cell tumor
10.3760/cma.j.issn.1673-4408.2010.04.012
- VernacularTitle:儿童生殖细胞肿瘤标志物研究进展
- Author:
Xiang LI
- Publication Type:Journal Article
- Keywords:
Tumor marker;
Germ cell tumor;
Children
- From:
International Journal of Pediatrics
2010;37(4):372-374
- CountryChina
- Language:Chinese
-
Abstract:
Tumor marker is a hot subject of research in oncology field,which would promote the diagnosis and treatment in clinic.Tumor markers of children's germ cell tumor include α-fetoprotein,glypican 3,SALL4,glial cell line-derived neurotropic factor receptorα-1(GFRα-1),Ki-67,octamer-binding transcription factor4,CD117,D2-40 and CD30.SALL4 would be used as a new tumor marker for germ cell tumor,specially for yolk sac tumor.GFRα-1 can be helpful for the diagnosis of immature teratoma.
