Tumor suppressor 1 of lung cancer in tumor genesis and development
10.3760/cma.j.issn.1673-422X.2010.04.003
- VernacularTitle:肺癌肿瘤抑制因子1与肿瘤的发生发展
- Author:
Jiongyu CHEN
;
Chaoqun HONG
- Publication Type:Journal Article
- Keywords:
Neoplasm metastasis;
Genes,tumor suppressor
- From:
Journal of International Oncology
2010;37(4):249-251
- CountryChina
- Language:Chinese
-
Abstract:
Tumor suppressor of lung cancer 1 (TSLC1) mediates cell-cell and cell-extracellar matrix adhesion, cellular signal transduction and immunoregulation, and additionally plays a vital role in inhibiting proliferation, migration and metastasis of tumor cells. As a novel tumor suppressor gene, TSLC1 may be regarded as a potential molecular marker for diagnosis and a pharmaceutical target. Consequently, to explore the functions and mechanism of TSLC1 in initiation and development of carcinomas has become one of the popular researches currently.
