Spontaneous clearance of high risk human papillomavirus infection
10.3760/cma.j.issn.0529-567x.2010.07.008
- VernacularTitle:高危型人乳头状瘤病毒感染的自然清除状况分析
- Author:
Wenying ZHANG
;
Chengbin MA
;
Jinyin XIAO
;
Hongrong ZHOU
- Publication Type:Journal Article
- Keywords:
Papillomavirus infections;
Papillomaviridae;
Cervical intraepithelial neoplasia;
Remission,spontaneous
- From:
Chinese Journal of Obstetrics and Gynecology
2010;45(7):515-518
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clearance of high risk human papillomavirus(HPV)infection among the women with normal cervical pathologic diagnosis.Methods One hundred and seventy.two HPV-positive cases with normal cervical pathologic diagnosis were enrolled in the study.The infection status of HPV was monitored during follow-up from Aug 2006 to Aug 2008.The time of HPV infection spontaneous clearance,as well as effect factors,were analyzed.Results During follow-up,there were 62.2%(107 cases,107/172) of the HPV infection cleared.The medium clearance time was 11.3 months(95% CI:10.6-16.6 months).The medium clearance time of aged<30 years,30-39 years,40-49 years and>49 years were 11.3,12.0,10.9 and 8.5 months.respectively.There were not significant difference among aged intervals (P=0.384).The virus copies of HPV-clearance cases and persistent-infection were 22.6 and 95.0,respectively.There was not significant difference between groups(P=0.061).Conclusions Most of the high risk HPV infection with normal cervical pathologic diagnosis would spontaneously cleared.Age and HPV copies may play little role in the HPV clearance.
