Interventional treatment of hepatocellular carcinoma complicated by Budd-Chiari syndrome
10.3760/cma.j.issn.1005-1201.2010.08.015
- VernacularTitle:布加综合征合并肝细胞癌的介入治疗
- Author:
Qingqiao ZHANG
;
Maoheng ZU
;
Hao XU
;
Yuming GU
;
Ning WEI
;
Wei XU
;
Hongtao LIU
;
Yanfeng CUI
;
Wenliang WANG
- Publication Type:Journal Article
- Keywords:
Budd-Chiari syndrome;
Carcinoma,hepatocellular;
Angioplasty;
Embohzation,therapeutic
- From:
Chinese Journal of Radiology
2010;44(8):852-855
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of interventional therapy for hepatocellular carcinoma complicated by Budd-Chiari syndrome. Methods Clinical data and imaging studies of 17 patients with hepatocellular carcinoma complicated by Budd-Chiari syndrome were retrospectively analyzed. Budd-Chiari syndrome was diagnosed by color Doppler ultrasound and confirmed by cavography in 17 patients. Hepatocellular carcinoma was diagnosed by fine-needle aspiration cytology in 5 patients,and by color Doppler ultrasound, computed tomography and /or MRI, and elevated level of alpha-fetoprotein in 12 patients. Both percutaneous transluminal angioplasty for treatment of obstruction of the inferior vena cava and transcatheter arterial chemoembolization (TACE) for hepatocellular carcinoma were performed in all patients. During follow-up, the tumor size, liver function, serum alpha-fetoprotein level and the recanalized inferior vena cava were evaluated by liver ultrasound, CT and laboratory examination. t test was used to compare the pressure. Results Thirty-nine interventional procedures were performed in 17 patients and all operations were successful without complications. Over the follow-up period of 2 to 90 months after percutaneous transluminal angioplasty in 17 patients, re-occlusion of inferior vena cava occurred in only one patient, which was redilated successfully. Following TACE, all 17 patients survived at two months followup, 13 patients survived at 6 months follow-up, 10 patients survived at 1 year follow-up, 5 patients survived at 2 years follow-up. The pressure of vena cava was (20.5±2.1) cm H2O (1cm H2O=0.098 kPa) before the interventional theraphy, while it was (3.6±1.0) cm H2O after it (t=30.32, P＜0.05). Conclusion Interventional therapy can be effectively performed for treatment of hepatocellular carcinoma complicated by Budd-Chiari syndrome.
