Perineural invasion of cholangiocarcinoma
10.3760/cma.j.issn.1673-4203.2010.07.017
- VernacularTitle:胆管癌周围神经浸润的研究进展
- Author:
Yujie FENG
;
Bingyuan ZHANG
;
Yun LU
- Publication Type:Journal Article
- Keywords:
Cholangiocarcinoma;
Perineural invasion;
Nerve growth factor;
Neural cell adhesion molecule;
Matrix metalloproteinase;
Neurotransmitter;
Transforming growth factor
- From:
International Journal of Surgery
2010;37(7):479-483
- CountryChina
- Language:Chinese
-
Abstract:
Cholangiocarcinoma is a type of malignant tumor with high destruction.Due to its low diagnostic rate and high fatality rate,the operation is the unique therapeutic methods for the radical cure.However,the diagnosis and treatment for the disease were always in the phase of progression,so currently,the radical therapeutic rate is quite low,while the recurrence rate of the operation is extremely high.If the correlated mechanism of perineural invasion of cholangiocarcinoma could be understood,then interrupted its perineural invasion in the early period,that could greatly enhance the prognosis of cholangiocarcinoma patients.This article systematically reviews the progress of cholangiocarcinoma neural invasion related molecules and possible mechanism.
