Functions of tumor-testis antigen and its application for tumor immunotherapy
10.3760/cma.j.issn.1673-422X.2010.06.010
- VernacularTitle:肿瘤-睾丸抗原的功能与肿瘤免疫治疗
- Author:
Liyan LIN
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Immunotherapy;
Cancer-testis antigens
- From:
Journal of International Oncology
2010;37(6):432-435
- CountryChina
- Language:Chinese
-
Abstract:
Cancer-testis antigen (CTA) is a kind of tumor-associated antigen, which expresses in various types of human tumor tissues but only express in a few of normal tissues. The CTA has numerous functions that not yet are fully understood. The CTA possesses immunogenicity that may induce cellular and humoral responses in vivo, which can provide a new approach for cancer immunotherapy.