Prospect for research on cyclin E and p27 in breast cancer
10.3760/cma.j.issn.1673-422X.2010.06.014
- VernacularTitle:cyclin E与p27在乳腺癌中的研究进展
- Author:
Yuejun ZHANG
;
Xuejian GAO
- Publication Type:Journal Article
- Keywords:
Cell cycle;
Cyclin E;
Cyclin-dependent kinase inhibitor p27;
Breast neoplasms
- From:
Journal of International Oncology
2010;37(6):445-448
- CountryChina
- Language:Chinese
-
Abstract:
Deregulation of cell cycle is one of important mechanisms leading to breast cancer. It has been revealed that cyclin E and p27 are the most important regulatory factor for cell cycle control and a better marker for evaluating prognosis of breast cancer compared to other biological markers.