Research review about inflammation promoting neoplasm metastasis
10.3760/cma.j.issn.1673-422X.2010.06.007
- VernacularTitle:炎症促发肿瘤转移的研究进展
- Author:
Chao LIU
;
Yuan HUANG
- Publication Type:Journal Article
- Keywords:
Inflammation;
Neoplasm metastasis
- From:
Journal of International Oncology
2010;37(6):422-425
- CountryChina
- Language:Chinese
-
Abstract:
In the tumor microenvironment, inflammatory cells regulate intracellular signaling transduction mediated by the corresponding nuclear transcription factor by releasing inflammatory factors ,which leads to transformation of epithelial cells to mesenchymalcellsand eventually promote tumor metastasis. Because of the intimate relationship between inflammation and tumor metastasis , it would be helpful for further enhancement of effectiveness of tumor therapy if we could better understand both the biological character of tumor and the related inflammatory factors.
