Mesenchymal stem cells as cellular vehicles for tumor gene therapy
10.3760/cma.j.issn.1673-422X.2010.06.008
- VernacularTitle:间充质干细胞作为肿瘤基因治疗载体的研究进展
- Author:
Zhe HAN
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Therapy;
Mesenchymal stem cells
- From:
Journal of International Oncology
2010;37(6):425-428
- CountryChina
- Language:Chinese
-
Abstract:
The conventional approach of systemic viral gene delivery is often associated with limited therapeutic efficacy and toxicity because of a lack of tumor specificity. Mesenchymal stem cells have the tumortracking abilities which provide possibility that the stable and high level of anti- cancer gene expression could be acquired within local tumor and a novel approach for better tumor-targeted gene delivery.
