Study on 746 cases of pituitary adenomas treated with surgery

VernacularTitle:746例经手术治疗的垂体腺瘤患者临床资料分析
Author: Minxian SUN ; Muxun ZHANG ; Ting LEI ; Fen ZHOU ; Lili WU ; Sisi YANG ; Chen DONG
Publication Type:Journal Article
Keywords: Pituitary adenomas; Diagnosis; Immunohistochemistry; Invasive
From: Chinese Journal of Endocrinology and Metabolism 2010;26(8):657-661
CountryChina
Language:Chinese
Abstract: Objective To analyze the clinical data, including clinical features, treatment, and prognosis,in patients with different kinds of pituitary adenomas. Methods In this retrospective study, 746 cases were included. The characteristics of general epidemiology, clinical symptoms, pathology, imaging, treatment, and prognosis were analyzed. Results Clinical features were different among various pituitary adenomas. Symptoms caused by mass effect and hormone abnormality were expresssed in varying degrees. Serum prolactin>121.28 μg/L can differentiate the prolactin adenoma from the other huge tumor causing hyperprolactinemia due to the mass effect. There is significant relationship between the size and the various types of pituitary adenomas ( P<0.01 ),also between the size and the invasive capability ( P<0.01 ). Conclusions The pituitary adenomas may have their specific epidemiological, clinical, pathological, and imaging features, due to the distinct biological behavior. It is necessary to do the diagnosis, treatment, and prognosis evaluation individually.