Nonfunctional Parathyroid Carcinoma: A Case Report.
10.3857/jkstro.2010.28.2.111
- Author:
Sang Gyu CHOI
1
Author Information
1. Department of Radiation Oncology, Dankook University Hospital, Cheonan, Korea. am2ran@hanmail.net
- Publication Type:Case Report
- Keywords:
Nonfunctional parathyroid carcinoma;
Radiotherapy
- MeSH:
Accounting;
Hypercalcemia;
Hyperparathyroidism;
Neoplasm, Residual;
Parathyroid Hormone;
Parathyroid Neoplasms;
Recurrence
- From:The Journal of the Korean Society for Therapeutic Radiology and Oncology
2010;28(2):111-116
- CountryRepublic of Korea
- Language:English
-
Abstract:
Parathyroid carcinoma is a rare endocrine malignancy accounting for 0.5% to 4.0% of all cases of hyperparathyroidism and commonly present as hypercalcemia and parathyroid hormone (PTH) elevation. Nonfunctional parathyroid carcinoma does not show symptoms of hyperparathyroidism and only showed a vague indication of being pathologic, even when detected late. The optimal treatment is en bloc resection of the cancer, but frequent local recurrence after surgery has been reported. Adjuvant local treatment such as radiotherapy may improve the likelihood local control in cases with incompletely resected or microscopic residual tumor. The results of this study point to a case of nonfunctional parathyroid carcinoma treated by external beam radiotherapy after en-bloc resection of cancer.
