KCNJ11 gene mutation in 3 cases with neonatal diabetes mellitus

VernacularTitle:三例新生儿糖尿病KCNJ11基因突变分析
Author: Yanmei SANG ; Guichen NI ; Yi GU ; Min LIU
Publication Type:Journal Article
Keywords: Neonatal diabetes mellitus; KCNJ 11 gene; ATP-sensitive K channel
From: Chinese Journal of Endocrinology and Metabolism 2010;26(8):682-683
CountryChina
Language:Chinese
Abstract: KCNJ11 gene mutation was searched in 3 families with neonatal diabetes. A KCNJ11 175 G>A (V59M) mutation was found in one child, while no KCNJ11 gene mutation was found in his parents. No mutation was found in the other two families. The result indicated that KCNJ11 gene mutation might lead to the onset of neonatal diabetes mellitus in Chinese.