Gastrointestinal dysfunction and gastrointestinal protection in children
10.3760/cma.j.issn.1673-4912.2010.04.037
- VernacularTitle:小儿胃肠功能障碍与胃肠保护
- Author:
Yiping ZHOU
- Publication Type:Journal Article
- Keywords:
Gastrointestinal dysfunction;
Gastrointestinal protection;
Children
- From:
Chinese Pediatric Emergency Medicine
2010;17(4):369-371
- CountryChina
- Language:Chinese
-
Abstract:
Gastrointestinal dysfunction is abnormalities of digestion and absorption caused by various reasons, which manifests bacterial colonization of the gastrointestinal tract, bacterial/endotoxin translocation,gastrointestinal mucosal barrier injury and immune disorders. Child and newborn gastrointestinal dysfunction/failure is secondary to the severe syndrome of critical illness, always be a part of multiple organ dysfunction syndrome. Structure and function of the gastrointestinal tract are significantly different between child and adult. The key therapy strategy of gastrointestinal dysfunction are maintenance of intestinal barrier, reconstruction of intestinal continuity, adjust of homeostasis, circulation and oxygen supply, and management of the primary disease on time.