Liver regeneration and bile acids metabolism
10.3760/cma.j.issn.1673-4203.2010.08.012
- VernacularTitle:肝再生与胆汁酸代谢
- Author:
Xiushan DONG
;
Haoliang ZHAO
- Publication Type:Journal Article
- Keywords:
Liver;
Regeneration;
Bile acids
- From:
International Journal of Surgery
2010;37(8):537-540
- CountryChina
- Language:Chinese
-
Abstract:
The liver regeneration is closely related to the bile acids. To avoid the toxic effects of bile acids on hepatocyte, the state of bile secretion, the rate-limiting enzyme of the bile acid synthesis, bile acids composition as well as the transporter changes at the process of liver regeneration. In vivo and in vitro experiments show that bile acids can promote liver cell proliferation, liver regeneration may be related to the signal which is released under the bile acid imbalance. The relationship between the liver regeneration and bile acid metabolism has an important practical significance in liver regeneration.
