The diagnosis and surgical treatment of hepatolithiasis associated with cholangiocarcinoma
10.3760/cma.j.issn.1008-6706.2010.14.006
- VernacularTitle:肝胆管结石合并肝胆管癌的诊断及手术治疗
- Author:
Xinfeng LAI
;
Lianghui LIN
;
Maozhong ZHANG
- Publication Type:Journal Article
- Keywords:
Hepatolithiasis;
Cholangiocarcinoma;
Diagnosis;
Surgical treatment
- From:
Chinese Journal of Primary Medicine and Pharmacy
2010;17(14):1883-1884
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore into the relationship between the hepatolithiasis and the intrahepatic cholangiocarcinoma, and summarize the experience of early diagnosis and surgical treatment of these disease. Methods A retrospective clinical analysis was made in 28 cases of hepatolithiasis complicated by intrahepatic cholangiocarcinoma from September 1998 to December 2008. Results It was found that the incidence of cholangiocarcinoma in hepatolithiasis was 5.9%. The correct rate of preoperative ultrasonic diagnosis was 57.15% ( 16/28 ) ,and that of CT diagnosis was 46.43 % ( 13/28), and that of MRCP diagnosis was 40.00% (6/15). 12 cases were radically resected,12 cases were treated by palliative therapy, and 4 cases were examined only with biopsy, and all cases were followed up. The 1-,2-,and 3-year survival rate in radical surgery were 83.34% ,58.34% ,25.00% respectively. And the 1-year,and 2-year survival rate in palliative surgery group were 66.67% ,8.33% respectively. And all the cases examined only with biosy died in 6 months after the biosy. Conclusion Cholangiocarcinoma is related to hepatolithiasis. In patients of hepatolithiasis who were older than 40 years and have a long history of recurrent cholangitis, weight-loss in a short period, progressive jaundice, or intractable abdominal pain,the possibility of accompanying cholangiocarcinoma should be considered. The key of improving the therapeutic effectiveness was early diagnosis ,early treatment and striving for radical operation.
