Effects of 860 MHz microwave on context conditioned fear in mice
10.3760/cma.j.issn.1674-6554.2010.08.002
- VernacularTitle:860 MHz微波辐射对小鼠场景性条件恐惧的影响
- Author:
Bing WU
;
Bo HU
;
Jianfeng SUI
- Publication Type:Journal Article
- Keywords:
Microwave;
Context conditioned fear;
Freezing
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2010;19(8):677-679
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of 860MHz microwave on the formation and extinction of context conditioned fear in mice. Methods The mice were exposed to 860MHz continuous microwave ( power density were 380 μW/cm2 or 550 μW/cm2, respectively) for 30 min or 2 h, which then were divided in to 5 groups.Each group consisted of 15 animals. Footshocks were used to induce context conditioned fear by 75 voltages. The frequency and time of freezing after irradiation were investigated. Results When 24 h after foot shocking, the values of freezing time: control group was 2.31 ±4. 17 , two groups of the microwave irradiation 2 h were 3.93 ±6.99 and 2.47 ± 3.34, the Nemenyi test results (P = 0.004): control group was 32.63333, while two groups of the microwave irradiation 2 h were 52.46667 and 39.76667; and the values of freezing frequency: control group was 0.73 ± 1.16 , two groups of the microwave irradiation 2 h were 0.86 ± 1.41 and 1.07 ± 1.16, the Nemenyi test results of (P=0. 014): control group was 33. 26667, while two groups of the microwave irradiation 2 h were 50. 76667 and 40.90000. Conclusion The mice receiving relatively longer period of microwave irradiation showed more stable memory of the context conditioned fear.
